(ABCNEWS.GO) — Circumcision may help reduce the risk of prostate cancer, according to a new study published in the journal Cancer.

A new analysis of 3,399 men found that those who were circumcised before their first sexual encounter saw a “significant” 15 percent decreased risk of developing prostate cancer compared with men who were uncircumcised or circumcised after the first time they had sex.

Prior research has found that men who are circumcised are at lower risk of infections like HPV and herpes. Since infections have been linked to an increased risk of prostate cancer, researchers said the findings fit in with past research on the subject.

“This observation is consistent with accumulating evidence that infection [and] inflammation in the prostate may play a role in the development of this disease,” said Janet Stanford, lead author of the study and co-head of the program in Prostate Cancer Research at the Fred Hutchinson Cancer Researcher Center in Seattle.

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