(TELEGRAPH) — It was known that grapefruit can cause adverse reactions when combined with certain drugs, but now doctors say the risks are greater than previously thought.

The fruit can cause death, acute kidney failure, respiratory failure, gastrointestinal bleeding, bone marrow suppression in immunocompromised people, renal toxicity and other serious side effects because of its interactions with drugs.

There are more than 85 drugs that may interact with grapefruit, and 43 can have serious side effects.

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