(San Jose Mercury) In a high-profile Silicon Valley split that comes amid reports of a complicated office romance, Google (GOOG) co-founder Sergey Brin has separated from his wife, biotech entrepreneur Anne Wojcicki.

The surprising development was not widely known until Wednesday, but a representative for the couple confirmed to this newspaper: “Anne and Sergey have been living apart for several months. They remain good friends and partners.” The couple has two children and until recently lived in Los Altos Hills.

Brin and Wojcicki, both 40, are highly influential figures in the tech industry and also rank among Silicon Valley’s biggest donors to charity. Brin is one of the world’s wealthiest men and, with Google co-founder Larry Page, one of two controlling shareholders in the giant Internet company.

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