JAMA study: Pfizer COVID shot’s protection fades in weeks

By Art Moore

Joe Biden delivers remarks on the FDA giving full approval to the Pfizer COVID-19 vaccine, Monday, Aug. 23, 2021, in the South Court Auditorium in the Eisenhower Executive Office Building at the White House. (Official White House photo by Adam Schultz)
Joe Biden delivers remarks on the FDA giving full approval to the Pfizer COVID-19 vaccine, Monday, Aug. 23, 2021, in the South Court Auditorium in the Eisenhower Executive Office Building at the White House. (Official White House photo by Adam Schultz)

A peer-reviewed paper published by the Journal of the American Medical Association concluded that immunity against the omicron coronavirus variant fades rapidly after a second and third dose of the Pfizer-BioNTech vaccine.

The research by Danish scientists published in JAMA Network Open on Friday found antibody responses fell within weeks after second and third Pfizer doses, Forbes reported.

The proportion of antibodies dropped from 76% four weeks after the second shot to 19% at weeks 12 to 14. The antibodies dropped even faster after the third dose, the booster shot.

Between the third and eighth week, antibodies fell 5.4-fold for omicron.

Last week, in a segment on “Good Morning America,” ABC News chief medical correspondent Dr. Jennifer Ashton warned it’s possible that repeated boosting actually can weaken the immune system.

She said that getting a booster shot is a good idea for older people who have chronic underlying conditions.

“But everyone else, don’t think that more boosting is the answer,” Ashton said. “We don’t know that that’s the case yet.”

Last month a top FDA official said a fourth COVID booster shot should be seen as a “stop gap” measure, concluding “we simply can’t be boosting people as frequently as we are.”

Meanwhile, CDC and U.K. government data have indicated that the COVID-19 vaccines not only are ineffective in preventing cases and transmission, they rapidly lose protection against severe illness or death while posing risks.

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A newly published long-term study by the prestigious British journal The Lancet that followed up on participants in the Moderna and Pfizer trials found the vaccines had no effect on overall mortality.

An analysis of CDC data by Dr. Meryl Nass found vaccinated Californians and New Yorkers were three times more likely to develop COVID than those who had prior immunity and were unvaccinated.

Further, vaccinated Californians had a higher rate of hospitalizations than those who were unvaccinated but had prior immunity. New York did not provide hospitalization data.

In April, the Food and Drug Administration released a briefing document that says the composition of the current COVID-19 vaccines might need to be changed to ensure high levels of protection.

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